KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRA2A
All Species:
25.76
Human Site:
Y196
Identified Species:
51.52
UniProt:
P08913
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08913
NP_000672.3
450
48957
Y196
E
I
N
D
Q
K
W
Y
V
I
S
S
C
I
G
Chimpanzee
Pan troglodytes
XP_521603
468
50335
G187
Y
V
I
S
S
C
I
G
S
F
F
A
P
C
L
Rhesus Macaque
Macaca mulatta
XP_001087738
450
49113
Y196
E
I
N
D
Q
K
W
Y
V
I
S
S
C
I
G
Dog
Lupus familis
XP_544018
622
67080
Y211
E
I
N
D
Q
K
W
Y
V
I
S
S
C
I
G
Cat
Felis silvestris
Mouse
Mus musculus
Q01338
450
48847
Y196
K
I
N
D
Q
K
W
Y
V
I
S
S
S
I
G
Rat
Rattus norvegicus
P22909
450
48921
Y196
K
I
N
D
Q
K
W
Y
V
I
S
S
S
I
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513049
394
43582
S174
I
L
T
V
W
V
I
S
A
V
I
S
F
P
P
Chicken
Gallus gallus
XP_426355
614
69002
Y370
K
L
N
D
E
T
W
Y
I
L
S
S
C
I
V
Frog
Xenopus laevis
P24628
442
49720
Y186
D
N
P
A
F
V
I
Y
S
S
I
V
S
F
Y
Zebra Danio
Brachydanio rerio
Q90WY4
388
43978
I168
M
K
K
S
E
G
D
I
C
D
I
N
K
E
K
Tiger Blowfish
Takifugu rubipres
P53453
463
52101
F190
C
F
I
A
N
P
A
F
V
V
Y
S
S
I
V
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200819
471
53401
Y213
V
I
S
E
D
I
G
Y
I
L
Y
S
T
M
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.6
96.4
58.5
N.A.
92.2
90.8
N.A.
45.5
43
33.3
60.4
32.6
N.A.
N.A.
N.A.
36
Protein Similarity:
100
86.1
96.6
62
N.A.
94
92.8
N.A.
53.1
51.2
50.6
70.6
49.4
N.A.
N.A.
N.A.
53
P-Site Identity:
100
0
100
100
N.A.
86.6
86.6
N.A.
6.6
53.3
6.6
0
20
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
13.3
100
100
N.A.
93.3
93.3
N.A.
20
86.6
13.3
13.3
33.3
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
0
0
9
0
9
0
0
9
0
0
0
% A
% Cys:
9
0
0
0
0
9
0
0
9
0
0
0
34
9
0
% C
% Asp:
9
0
0
50
9
0
9
0
0
9
0
0
0
0
0
% D
% Glu:
25
0
0
9
17
0
0
0
0
0
0
0
0
9
0
% E
% Phe:
0
9
0
0
9
0
0
9
0
9
9
0
9
9
0
% F
% Gly:
0
0
0
0
0
9
9
9
0
0
0
0
0
0
50
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
50
17
0
0
9
25
9
17
42
25
0
0
59
0
% I
% Lys:
25
9
9
0
0
42
0
0
0
0
0
0
9
0
9
% K
% Leu:
0
17
0
0
0
0
0
0
0
17
0
0
0
0
9
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
9
50
0
9
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
0
9
0
0
9
0
0
0
0
0
0
9
9
9
% P
% Gln:
0
0
0
0
42
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
9
17
9
0
0
9
17
9
50
75
34
0
0
% S
% Thr:
0
0
9
0
0
9
0
0
0
0
0
0
9
0
0
% T
% Val:
9
9
0
9
0
17
0
0
50
17
0
9
0
0
17
% V
% Trp:
0
0
0
0
9
0
50
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
67
0
0
17
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _